Intercellular Adhesion Molecule-1 (ICAM-1) Polymorphisms and Cancer Risk: A Meta-Analysis

Polymorphisms in the intercellular adhesion molecule 1 gene and cancer risk: a meta-analysis.

OBJECTIVES The correlation between intercellular adhesion molecule 1 (ICAM-1) common polymorphisms (rs5498 A>G and rs3093030 C>T) and cancer susceptibility has been explored in various ethnic groups and different cancer types; however, these investigations have yielded contradictory results. To address the relationship more precisely, we performed this meta-analysis. DESIGN AND METHODS EmBase...

Association between the Polymorphisms in Intercellular Adhesion Molecule-1 and the Risk of Coronary Atherosclerosis: A Case-Controlled Study

Intercellular adhesion molecule-1 (ICAM-1), an important immune adhesion molecule, is related to the atherosclerosis. We explored the association between the polymorphisms of the ICAM-1 gene and coronary atherosclerotic stenosis to determine whether any risk factors correlate with genetic polymorphisms in Chinese patients with coronary atherosclerosis. Using the SNaPshot assay, we examined six ...

A Comparative Study of Serum Level of Vascular Cell Adhesion Molecule-1 (sVCAM-1), Intercellular Adhesion Molecule-1(ICAM-1) and High Sensitive C - reactive protein (hs-CRP) in Normal and Pre-eclamptic Pregnancies

Intercellular adhesion molecule 1 rs5498 polymorphism is associated with the risk of myocardial infarction

Several studies addressed the association between Intercellular adhesion molecule 1 (ICAM-1) rs5498 polymorphism and Myocardial Infarction (MI) risk. However, they addressed conflicting findings. Therefore, the aim of this study was to explore whether ICAM-1 gene rs5498 polymorphism plays an important role in modifying the risk of MI. A meta-analysis was conducted on the association between ICA...

Polymorphisms in the ICAM gene locus are not associated with breast cancer Risk.

In a recent case-control study which examined >25,000 single nucleotide polymorphisms (SNP), the intercellular adhesion molecule (ICAM) locus was proposed as a susceptibility locus for breast and prostate cancer (1). The genes ICAM1, ICAM4 , and ICAM5 are all located within a 20 kb region of high linkage disequilibrium of chromosome 19p13.2. We examined the association of three previously impli...